64 research outputs found

    GIS as integrating tool in sustainability and global change

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    Costs and benefits of spatial data accuracy on comprehensive conservation planning assessments - A conceptual approach

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    The planning of protected habitat networks to safeguard global biodiversity requires substantial knowledge on exposure, services, and functions of ecosystems. Spatial-ecological datasets contain important information for the adequate assessment of spatial economic and ecologic interdependencies. However, these data are still lacking in many places. Comprehensive earth observation can play an important role in the provision of such data but it also involves costs. Cost-benefit analyses may answer the question whether the preparation of such comprehensive spatial data is worthwhile and may help to find the appropriate data resolution for conservation planning questions under consideration of costs. We compare several wetland data sets on global, national, and regional scale according to their spatial accuracy of wetland distribution and the costs of data survey, monitoring, and supply. The spatial data are integrated into bioeconomic land use models of different scales to assess benefits and uncertainties of increased data resolution and accuracy

    The Value of Global Earth Observations

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    Humankind has never been so populous, technically equipped, and economically and culturally integrated as it is today. In the twenty-first century, societies are confronted with a multitude of challenges in their efforts to manage the Earth system

    Abacavir, efavirenz, didanosine, with or without hydroxyurea, in HIV-infected adults failing initial nucleoside/protease inhibitor-containing regimens

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    Background: Hydroxyurea (HU) is an immunomodulatory agent that has been documented to enhance the antiretroviral activity of nucleoside reverse transcriptase inhibitors, such as abacavir (ABC) and didanosine (ddI), and would be expected to improve virologic efficacy. Methods: A 48-week, phase IV, multicenter, open-label, proof-of-concept clinical trial was conducted to evaluate second-line, protease inhibitor (PI)-sparing therapy with ABC/efavirenz (EFV)/ddl plus HU or without HU in HIV-infected subjects failing to achieve HIV-1 RNA ù‰€ 400 copies/mL after ù‰„ 16 weeks of treatment with lamivudine /zidovudine or lamivudine/stavudine, plus 1 or 2 Pls. Subjects were assigned to ABC (300 mg twice daily)/ EFV (600 mg once daily)/ ddI (400 mg once daily) plus HU (500 mg twice daily) (n = 30) or this regimen without HU (n = 24). Results: Baseline mean HIV-1 RNA was 3.86 log10 copies/mL and CD4+ cell count was 345 cells/mm3. A similar percentage of subjects in the non-HU arm (58%) and HU arm (53%) completed the study. Intent-to-treat: missing = failure analysis showed no differences in proportions of subjects in the non-HU and HU arms achieving undetectable plasma HIV-1 RNA levels at week 24 (<400 copies/mL: 58% [14/24] vs 57% [17/30], P = 0.899; <50 copies/mL (50% [12/24] vs 47% [14/30], P = 0.780). Median change from baseline in CD4+ cell count in the non-HU and HU arms at week 48 was +114 cells/mm3 and -63 cells/mm3 (P = 0.007), respectively. Both regimens were generally well tolerated, although more subjects in the HU arm withdrew prematurely from the study due to adverse events (23% vs 4%). Four cases of possible ABC-related hypersensitivity were observed. Conclusion: ABC/EFV/ddI was an effective and well-tolerated second-line regimen for nucleoside/PI-experienced HIV-infected subjects. The addition of HU blunted the CD4+ cell response, did not appear to enhance antiviral activity, and resulted in more treatment-limiting adverse events

    Multiple dimensions of biodiversity drive human interest in tide pool communities

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    Abstract Activities involving observation of wild organisms (e.g. wildlife watching, tidepooling) can provide recreational and learning opportunities, with biologically diverse animal assemblages expected to be more stimulating to humans. In turn, more diverse communities may enhance human interest and facilitate provisioning of cultural services. However, no experimental tests of this biodiversity-interest hypothesis exist to date. We therefore investigated the effects of different dimensions of animal biodiversity (species richness, phyletic richness and functional diversity) on self-reported interest using tide pools as a model system. We performed two experiments by manipulating: (1) the richness of lower (species) and higher taxonomic levels (phyla) in an image based, online survey, and (2) the richness of the higher taxonomic level (phyla) in live public exhibits. In both experiments, we further quantified functional diversity, which varied freely, and within the online experiment we also included the hue diversity and colourfulness arising from the combination of organisms and the background scenes. Interest was increased by phyletic richness (both studies), animal species richness (online study) and functional diversity (online study). A structural equation model revealed that functional diversity and colourfulness (of the whole scene) also partially mediated the effects of phyletic richness on interest in the online study. In both studies, the presence of three of four phyla additively increased interest, supporting the importance of multiple, diverse phyla rather than a single particularly interesting phylum. These results provide novel experimental evidence that multiple dimensions of biodiversity enhance human interest and suggest that conservation initiatives that maintain or restore biodiversity will help stimulate interest in ecosystems, facilitating educational and recreational benefits

    Spatial assessment of sea level rise on Martinique’s coastal zone and analysis of planning frameworks for adaptation

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    Accelerated sea level rise and hurricanes are increasingly influencing human coastal activities. With respect to the projected continuation of accelerated sea level rise and global warming one must count with additional expenses for adaptation strategies along the coasts. On the mountainous island Martinique the majority of settlements are situated along the coast almost at sea level. But potential rises in sea level and its impacts are not addressed in coastal management, even though saltwater intrusion and coastal erosion with increasing offshore loss of sediment are locally already a severe problem. At a sea level rise of 50 cm, one fourth of Martinique’s coastline will be affected by erosion and one fifth of the islands surface will have high probability to get flooded during coastal hazards. This is a growth of 5% of the impact area in comparison to present conditions. This article analyses potential adaptation strategies and argues that the development of a coastal zone management plan considering sea level rise and its impact area is of utmost importance. Empirical assessment models in combination with spatial analysis are useful in obtaining statements about coastal impacts concerning sea level rise. This paper sees itself as recommendation of action not only for Martinique
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